Nyxoid contains the active substance naloxone.1 Naloxone temporarily reverses the effects of opioids such as heroin, methadone, fentanyl, oxycodone, buprenorphine and morphine.2

Nyxoid is a single-dose nasal spray used for emergency treatment of opioid overdose or possible opioid overdose in adults and adolescents over 14 years. It is not a substitute for emergency medical care.



  1. Nyxoid SmPC, www.medicines.ie
  2. www.ema.europe.eu/en/medicines/human/EPAR/nyxoid